47 research outputs found

    Managing Web Services Security

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    Constitutivism

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    A brief explanation and overview of constitutivism

    Philosophy of action

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    The philosophical study of human action begins with Plato and Aristotle. Their influence in late antiquity and the Middle Ages yielded sophisticated theories of action and motivation, notably in the works of Augustine and Aquinas.1 But the ideas that were dominant in 1945 have their roots in the early modern period, when advances in physics and mathematics reshaped philosophy

    Genomic investigations of unexplained acute hepatitis in children

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    Since its first identification in Scotland, over 1,000 cases of unexplained paediatric hepatitis in children have been reported worldwide, including 278 cases in the UK1. Here we report an investigation of 38 cases, 66 age-matched immunocompetent controls and 21 immunocompromised comparator participants, using a combination of genomic, transcriptomic, proteomic and immunohistochemical methods. We detected high levels of adeno-associated virus 2 (AAV2) DNA in the liver, blood, plasma or stool from 27 of 28 cases. We found low levels of adenovirus (HAdV) and human herpesvirus 6B (HHV-6B) in 23 of 31 and 16 of 23, respectively, of the cases tested. By contrast, AAV2 was infrequently detected and at low titre in the blood or the liver from control children with HAdV, even when profoundly immunosuppressed. AAV2, HAdV and HHV-6 phylogeny excluded the emergence of novel strains in cases. Histological analyses of explanted livers showed enrichment for T cells and B lineage cells. Proteomic comparison of liver tissue from cases and healthy controls identified increased expression of HLA class 2, immunoglobulin variable regions and complement proteins. HAdV and AAV2 proteins were not detected in the livers. Instead, we identified AAV2 DNA complexes reflecting both HAdV-mediated and HHV-6B-mediated replication. We hypothesize that high levels of abnormal AAV2 replication products aided by HAdV and, in severe cases, HHV-6B may have triggered immune-mediated hepatic disease in genetically and immunologically predisposed children

    Financial distress and perceived stress among university students in Health Sciences

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    College or university life is a period of significant life transition typically marked by an increase in financial responsibility. Lack of economic support and financial distress are rising concerns at many higher learning institutions today and can be a potential stress factor for many students. The aim of this study was to determine the financial status, levels of financial distress, perceived stress and life satisfaction among university students studying health-related fields. This was a cross-sectional study conducted among 100 undergraduate students from the Faculty of Pharmacy (n=35), Faculty of Health Sciences (n=36) and Faculty of Dentistry (n=29). The In-Charge Financial Distress/Financial Wellbeing scale, Perceived Stress Scale and Satisfaction with Life Scale questionnaires were used to determine perceived financial distress and stress, as well as life satisfaction respectively. In addition, socioeconomic and demographic data were also collected. Data analysis included comparing levels of financial distress, perceived stress, as well as life satisfaction among sociodemographic factors, as well as associations between financial distress with perceived stress and life satisfaction. The study respondents were consisted of 2nd (n=35), 3rd (n=32) and 4th (n=33) year students. A majority of the respondents were Malays (44%), followed by Chinese (38%), and Indians (12%). About 46% of the respondents were fully dependent on scholarships or PTPTN loans, 24% were funded by parents while the rest either received part study loans or funded by both scholarships/loans and parents. The average total monthly expenditure was reported to be RM 717 ± 296. The highest monthly expenditures were recorded among Chinese students (RM 816 ± 286) compared to the rest. The mean scores for financial distress, perceived stress and life satisfaction were 5.8 ± 1.9 (CI: 5.4 – 6.2), 21.2 ± 5.6 (CI: 20.1 – 22.3) and 22.2 ± 5.4 (CI: 21.1 – 23.2) respectively. Overall, the students in the study showed moderate levels of financial distress and perceived stress. Correlation analysis indicated that greater financial distress was associated with greater perceived stress. Factors impacting university students’ financial distress should be investigated along with ways to overcome them in future studies

    A study and evaluation of the old and new bankruptcy acts.

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    Bankruptcy is a statute defined procedure allowing for the orderly repayment and release of debts. It is a situation which every person hopes to avoid. In the unfortunate event that a person is made bankrupt, bankruptcy brings forth many restrictions while carrying a social stigma. In Singapore, bankruptcy laws were previously governed by the old Bankruptcy Act for over a hundred years. A total revamp of bankruptcy law was enacted in July 1995 with the introduction of the new Bankruptcy Act. The new Act brought forth many changes in bankruptcy law that were viewed by many as long overdue. It was warmly received as the old Act was very outmoded and archaic when viewed in today’s context. This study aims to provide the reader with an insight into the salient features of the old and new Acts. We will introduce to the reader the shortcomings of the old Act and the rationale for the formulation of the new Act. We hope that after reviewing our report, the reader will be better able to comprehend the workings of the bankruptcy law in Singapore. ATTENTION: The Singapore Copyright Act applies to the use of this document. Nanyang Technological University LibraryACCOUNTANC

    Deliver

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    Deliver is a student crime drama film, produced as a final year thesis project by Inverted Commas Productions. The team consists of four Nanyang Technological University undergraduates from the Wee Kim Wee School of Communication and Information: Yap Chia Shen, Khoo Kai Wen Kenny, Jett Yeo, and Lee Soong Liang, Peter. This report will delve into the filmmaking process behind Deliver, from the beginning of conception to the ending of post-production.Bachelor of Communication Studie
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